Aspirin

BRAND & GENERIC NAMES

4-Way Cold Tablets Emagrin
8-Hour Bayer Timed Release Empirin
Acetophen Empirin Compound
Acetylsalicylic Acid Empirin Compound w/Codeine
Alka Seltzer Emprazil
Alka-Seltzer Effervescent Entrophen
Pain Reliever & Antacid Equagesic
Aluminum ASA Excedrin
Amytal and Aspirin Fiorinal
Anacin Fiorinal w/Codeine
Anaphen Hiprin
Ancasal Histadyl and ASA Compound
Anexsia w/Codeine Hyco-Pap
A.P.C. ICN 65 Compound
A.P.C. w/Codeine Kengesin
Apo-Asen Lanorinal
Arthinol Lemidyne w/Codeine
Arthritis Bayer, Timed-Release Magnaprin
Arthritis Pain Formula Maprin
A.S.A. Maprin I-B
A.S.A. & Codeine Compound Measurin
A.S.A. Compound Mepro Compound
A.S.A. Enseals Metrogesic
Ascodeen-30 Mobidin
Ascriptin Norgesic
Ascriptin A/D Norwich Aspirin
Ascriptin w/Codeine Nova-Phase
Asperbuf Novasen
Aspergum Pabirin Buffered
Aspir-10 P-A-C Compound
Aspirin Compound w/Codeine P-A-C Compound w/Codeine
Aspirjen Jr. Pargesic Compound 65
Astrin Percodan
Axotal Persistin
Bancap w/Codeine Phenodyne w/Codeine
Bayer Poxy Compound-65
Bayer Timed-Release Presalin
Arthritic Pain Formula Progesic Compound-65
Bexophene Propoxychel Compound
Buff-A Propoxyphene HCl Compound
Buff-A-Comp Repro Compound 65
Buffaprin Rhinocaps
Buffered ASA Riphen-10
Bufferin Safety Coated APF
Buffex Arthritis Pain Formula
Buffinol St. Joseph
Buf-Tabs St. Joseph Aspirin for
Calciphen Children
Cama Arthritis Reliever Sal-Adult
Cama Inlay Salatin
Causalin Salatin w/Codeine
Cefinal Saleto
Cirin Salimeph Forte
Codalan Sal-Infant
Codasa Salocol
Congespirin Salsprin
Coricidin D Soma5Compoundd
Coryphen Soma Compound w/Codeine
Cosprin Stero-Darvon
Darvon Compound Supac
Dasicon Supasa
Decagesic Synalgos
Dia-Gesic Talwin Compound
Dihydrocodein Compound Triaminic
Dolene Compound-65 Triaphen-10
Dolor Trigesic
Dolprn Vanquish
Dynosal Verin
Easprin Wesprin Buffered
Ecotrin Zorprin
Elder 65 Compound

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BASIC INFORMATION

Habit forming? No
Prescription needed? No
Available as generic? Yes
Drug class: Analgesic, anti-inflammatory (salicylate)

USES

Reduces pain, fever, inflammation.
Relieves swelling, stiffness, joint pain of arthritis or rheumatism.
Antiplatelet effect.

DOSAGE & USAGE INFORMATION

How to take:

Tablet or capsule - Swallow with liquid.
Extended-release tablets or capsules - Swallow each dose whole.
Effervescent tablets - Dissolve in water.
Chewing gum tablets - Chew completely. Don't swallow whole.
Suppositories - Remove wrapper and moisten suppository with water. Gently insert into rectum, large end first.
When to take: Pain, fever, inflammation - As needed, no more often than every 4h ours.
If you forget a dose: Pain, fever - Take as soon as you remember. Wait 4 hours for next dose.
Arthritis - Take as soon as you remember up to 2 hours late. Return to regular schedule.
What drug does: Affects hypothalamus, the part of the brain which regulates temperature by dilating small blood vessels in skin.
Prevents clumping of platelets (small blood cells) so blood vessels remain open.
Decreases prostaglandin effect.
Suppresses body's pain messages.

Time lapse before drug works:

30 minutes for pain, fever, arthritis.
Don't take with: Any other medicines, even over-the-counter drugs such as cough and cold medicines, nose drops, diet pills, laxatives or
caffeine, without consulting your doctor.

OVERDOSE SYMPTOMS: Ringing in ears; nausea; vomiting; dizziness; fever; deep, rapid breathing; hallucinations; convulsions; coma.

WHAT TO DO: Dial 0 (operator) or 911 (emergency) for an ambulance or medical help. Then give first aid immediately.

POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS

SYMPTOMS WHAT TO DO

Life-threatening:

Black or bloody vomit;
blood in urine;
treatment immediately. difficulty breathing;
hives, rash, intense itching, faintness soon after a dose (anaphylaxis).

Common:

Nausea, vomiting. Discontinue. Seek emergency treatment.
Heartburn, Continue. Call doctor indigestion. when convenient.
Ringing in ears. Continue. Tell doctor at next visit.
Infrequent: None expected.

Rare:

Black stools, Discontinue. Seek unexplained fever. emergency treatment.
Rash, hives, itch, Discontinue. Call diminished vision, doctor right away. shortness of breath, wheezing, jaundice, mental confusion.
Drowsiness. Continue. Call doctor when convenient.

WARNINGS & PRECAUTIONS

Don't take if:

You need to restrict sodium in your diet. Buffered effervescent tablets and sodium salicylate are high in sodium.
You are sensitive to aspirin or aspirin has a strong vinegar- like odor, which means it has decomposed.
You have a peptic ulcer of the stomach or duodenum or a bleeding disorder.

Before you start, consult your doctor:

If you have had stomach or duodenal ulcers.
If you have had gout.
If you have asthma or nasal polyps.
- Pregnancy: Risk to unborn child outweighs drug benefits. Don't use. Infants & children:
- Overdose frequent and severe. Keep bottles out of children's reach.
- Consult doctor before giving to persons under age 18 who have fever and discomfort of viral illness, especially chickenpox and influenza. Probably increases risk of Reye's syndrome.
- Prolonged use: Kidney damage. Periodic kidney-function test recommended.
- Skin & sunlight: Aspirin combined with sunscreen may decrease sunburn.
- Driving or hazardous activities: No restrictions unless you feel drowsy.
- Discontinuing: For chronic illness - Don't discontinue without doctor's advice until you complete prescribed dose, even though symptoms diminish or disappear.
- Others: Aspirin can complicate surgery, pregnancy, labor and delivery, and illness.
- For arthritis:Don't change dose without consulting doctor.
- Urine tests for blood sugar may be inaccurate.

POSSIBLE INTERACTION WITH OTHER DRUGS

Acebutolol: Decreased antihypertensive effect of acebutolol.
ACE inhibitors: Decreased
ACE inhibitor: captopril, enalapril, lisinopril effect.
Allopurinol: Decreased allopurinol effect.
Antacids: Decreased aspirineffect.
Anticoagulants: Increased anticoagulant effect. Abnormal bleeding.
Antidiabetics (oral, Low blood sugar.
Aspirin (other): Likely aspirin toxicity.
Bumetanide: Possible aspirin toxicity.
Cortisone drugs: Increased cortisone effect. Risk of ulcers and stomach bleeding.
Ethacrynic acid: Possible aspirin toxicity.
Furosemide: Possible aspirin toxicity. May decrease furosemide effect.
Gold compounds: Increased likelihood o kidney damage.
Indomethacin: Risk of stomach bleeding and ulcers.
Ketoprofen: Increased risk of stomach ulcer.
Methotrexate: Increased methotrexate effect.
Minoxidil: Decreased minoxidil effect.
Non-steroidal: Risk of stomach
anti-inflammatory: bleeding and ulcers.
Oxprenolol: Decreased antihypertensive effect of oxprenolol.
Para-aminosalicylic: Possible aspirin
acid (PAS): toxicity.
Penicillins: Increased effect of both drugs.
Phenobarbital: Decreased aspirin effect.
Phenytoin: Increased phenytoin effect.
Probenecid: Decreased probenecid effect.
Propranolol: Decreased aspirin effect.
Rauwolfia alkaloids: Decreased aspirin effect.
Salicylates (other): Likely aspirin toxicity.
Spironolactone: Decreased spironolactone effect.
Sulfinpyrazone: Decreased sulfinpyrazone effect.
Terfenadine: May conceal symptoms of aspirin overdose, such as ringing in ears.
Vitamin C: Possible aspirin (large doses) toxicity.
Valproic acid: May increase valproic acid effect.

POSSIBLE INTERACTION WITH OTHER SUBSTANCES

Tobacco: None expected.

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Health Care