Sunday, June 26, 2022
HomeDiseaseBelladonna Alkaloids & Barbiturates

Belladonna Alkaloids & Barbiturates

source : pixabay

Brand & Generic Names

Antrocol Donna-Sed
ATROPINE & PHENOBARBITAL Donnatal
ATROPINE, HYOSCYAMINE, Donnatal Extentabs
SCOPOLAMINE & Donnatol No. 2
BUTABARBITAL Donphen
ATROPINE, HYOSCYAMINE, HYOSCYAMINE &
SCOPOLAMINE & PHENOBARBITAL
PHENOBARBITAL Hyosophen
Barbidonna Kinesed
Barbidonna 2 Levsin-PB
Barophen Levsin with Phenobarbital
Belladenal Levsinex with Phenobarbital
Belladenal-S Timecaps
Belladenal Spacetabs Malatal
BELLADONNA & AMOBARBITAL Pheno-Bella
BELLADONNA & BUTABARBITAL Relaxadon
Bellalphen Spaslin
Bellergal Spasmolin
Butibel Spasmophen
Chardonna-2 Spasquid
Donnamor Susano
Donnapine

BASIC INFORMATION

  • Habit forming? Yes
  • Prescription needed? Yes
  • Available as generic? Some yes, some no
  • Drug class: Antispasmodic, anticholinergic, sedative

USES

  • Reduces spasms of digestive system, bladder and urethra.
  • Reduces anxiety or nervous tension (low dose).
  • Relieves insomnia (higher bedtime dose).

DOSAGE & USAGE INFORMATION

  • How to take: Tablet, liquid or capsule–Swallow with liquid or food to lessen stomach irritation. If you can’t swallow whole, crumble tablet or open capsule and take with liquid or food.
  • Extended-release tablets or capsules– Swallow each dose whole.
  • Chewable tablets–Chew well before swallowing.
  • Drops–Dilute dose in beverage before swallowing. When to take: At the same times each day. If you forget a dose: Take as soon as you remember up to 2 hours late. If more than 2 hours, wait for next scheduled dose (don’t double this dose). What drug does:
  • May partially block nerve impulses at nerve-cell connections.
  • Blocks nerve impulses at parasympathetic nerve endings, preventing muscle contractions and gland secretions of organs involved.
  • Time lapse before drug works: 15 to 30 minutes.
  • Don’t take with: Any other medicines, even over-the-counter drugs such as cough and cold medicines, nose drops, diet pills, laxatives or caffeine, without consulting your doctor.

OVERDOSE

  • SYMPTOMS: Blurred vision, confusion, convulsions, irregular heartbeat, hallucinations, coma.
  • WHAT TO DO: Dial 0 (operator) or 911 (emergency) for an ambulance or medical help. Then give first aid immediately.

POSSIBLE ADVERSE REACTIONS OR SIDE EFFECTS

SYMPTOMS WHAT TO DO

  • Life-threatening: Unusual excitement, Seek emergency restlessness, fast treatment immediately. heartbeat, breathing difficulty.
  • Common: Dry mouth, throat, Discontinue. Call nose; drowsiness; doctor right away. constipation; dizziness; nausea; vomiting; “hangover” effect; depression; confusion.
  • Reduced sweating, Continue. Call doctor slurred speech, when convenient. agitation. Infrequent: Difficult urination; Discontinue. Call difficult swallowing; doctor right away. rash or hives; face, lip or eyelid swelling; joint or muscle pain. Rare: Jaundice; unusual Discontinue. Call bruising or bleeding; doctor right away. hives, skin rash; pain in eyes; blurred vision; sore throat, fever, mouth sores; unexplained bleeding or bruising.

WARNINGS & PRECAUTIONS

Don’t take if:

  • You are allergic to any barbiturate or any anticholinergic.
  • You have porphyria, trouble with stomach bloating, difficulty emptying your bladder completely, narrow-angle glaucoma, severe ulcerative colitis.

Before you start, consult your doctor:

  • If you have open-angle glaucoma, angina, chronic bronchitis or asthma, hiatal hernia, liver disease, enlarged prostate, myasthenia gravis, peptic ulcer, epilepsy, kidney or liver damage, anemia, chronic pain.
  • If you will have surgery within 2 months, including dental surgery, requiring general or spinal anesthesia. Pregnancy: Risk to unborn child outweighs drug benefits. Don’t use. Infants & children: Use only under doctor’s supervision.

Prolonged use:

  • May cause addiction, anemia, chronic intoxication.
  • May lower body temperature, making exposure to cold temperatures hazardous. Skin & sunlight: May cause rash or intensify sunburn in areas exposed to sun or sunlamp.

Driving or hazardous activities:
Don’t drive or pilot aircraft until you learn how medicine affects you. Don’t work around dangerous machinery. Don’t climb ladders or work in high places. Danger increases if you drink alcohol or take medicine affecting alertness and reflexes.

Discontinuing:
May be unnecessary to finish medicine. Follow doctor’s instructions. If you develop withdrawal symptoms of hallucinations, agitation or sleeplessness after discontinuing, call doctor right away.

Others: Great potential for abuse.

Possible Interaction with Other Drugs

GENERIC NAME COMBINED EFFECT
———————— ———————–
Acetaminophen Possible decreased barbiturate
effect.
Amantadine Increased belladonna effect.
Antacids Decreased belladonna effect.
Anticoagulants, Decreased anti-
oral coagulant effect.
Anticholinergics, Increased belladonna
other effect.
Anticonvulsants Changed seizure patterns.
Antidepressants, Possible dangerous
tricyclics (TCA) oversedation. Avoid.
Antidiabetics, Increased barbiturate
oral effect.
Antihistamines Dangerous sedation. Avoid.
Aspirin Decreased aspirin effect.
Attapulgite Decreased belladonna effect.
Beta-adrenergic Decreased effects of
blockers beta-adrenergic blocker.
Carteolol Increased barbiturate effect.
Dangerous sedation.
Central nervous Dangerous sedation. Avoid.
Contraceptives, Decreased contraceptive
oral effect.
Cortisone drugs Increased internal eye pressure.
Decreased cortisone effect.
Digitoxin Decreased digitoxin effect.
Doxycycline Decreased doxycycline effect.
Dronabinol Increased effects of both drugs.
Avoid.
Furosemide Possible orthostatic hypotension.
Griseofulvin Decreased griseofulvin effect.
Haloperidol Increased internal eye pressure.
Indapamide Increased indapamide effect.
Ketoconazole Decreased ketoconazole effect.
MAO inhibitors Increased belladonna and
barbiturate effect.
Meperidine Increased belladonna effect.
Methylphenidate Increased belladonna effect.
Metronidazole Decreased metronidazole effect.
Mind-altering drugs Dangerous sedation. Avoid.
Narcotics Dangerous sedation. Avoid.
Nitrates Increased internal eye pressure.
Nizatidine Increased nizatidine effect.
Non-steroidal Decreased anti-inflammatory effect.
Orphenadrine Increased belladonna effect.
Pain relievers Dangerous sedation. Avoid.
Phenothiazines Increased belladonna effect. Danger
of oversedation.
Pilocarpine Loss of pilocarpine effect in
glaucoma treatment.
Potassium Possible intestinal
supplements ulcers with oral potassium tablets.
Quinidine Increased belladonna effect.
Sedatives Dangerous sedation. Avoid.
Sleep inducers Dangerous sedation. Avoid.
Sotalol Increased barbiturate effect.
Dangerous sedation.
Tranquilizers Dangerous sedation. Avoid.
Valproic acid Increased barbiturate effect.
Vitamin C Decreased belladonna effect. Avoid
large doses of vitamin C.

Possible Interaction with Other Substances

INTERACTS WITH COMBINED EFFECT
————— —————
Alcohol: Possible fatal oversedation. Avoid.
Beverages: None expected.
Cocaine: Excessively rapid heartbeat. Avoid.
Foods: None expected.
Marijuana: Drowsiness and dry mouth. Avoid.
Tobacco: Decreased effectiveness of acid
reduction in stomach.

From the Complete Guide to Pediatric Symptoms, Illness & Medications by H. Winter Griffith, M.D. © 1989 The Putnam Berkley Group, Inc.; electronic rights by Medical Data Exchange.

Advertisingspot_img

Popular posts

My favorites

I'm social

0FansLike
0FollowersFollow
3,365FollowersFollow
0SubscribersSubscribe